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Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is really a Vietnamese traditionally medicinal plant found in treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. These studies aimed to research the effects of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The final results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the best antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (except for total flavonoids) and antioxidant capacity, when compared to conventional and ultrasound-assisted extractions. These data demonstrate that the use of methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application in the nutraceutical and/or pharmaceutical industries.

Drying methods, solvents and extraction methods greatly affect the phytochemical compounds and biological activity from plant materials. The aims on this study could determine the effects of various drying methods, various solvents and extraction methods around the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root from Vietnam. The results indicated that microwave drying was an efficient method in removal of water with regards to shortest drying time, lowest energy consumption and greatest retention of phytochemical compounds and antioxidant capacity in the P. trimera root while methanol and microwave-assisted extraction were the best solvent and way for greatest extraction with the phytochemical compounds and antioxidant capacity from the P. trimera root. The findings using this study allow retaining the very best amounts of phytochemical compounds and antioxidant capacity through the P. trimera root for potential application from the nutraceutical industry.

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